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Dr. Megan's Blog Education


Written by Dr. Megan Milne & Sheinese Clement

Prednisone is a medication that can be very helpful in treating various health conditions, but it may also have some side effects. Nutranize Zone is a special product designed to assist people in counteracting those side effects. One of its key ingredients is riboflavin. Let’s explore how riboflavin works and how it could benefit someone taking prednisone.

What is Riboflavin?

Riboflavin, commonly known as vitamin B2, belongs to the family of B vitamins, a group of eight essential nutrients that our bodies need to stay healthy. It can be found in foods like milk, eggs, green leafy vegetables, and whole grains. Our bodies cannot produce riboflavin on their own, so we must get it from the food we eat or through supplements like Nutranize Zone.

How Does Riboflavin Work?

Riboflavin plays a crucial role in many aspects of our health. It helps our bodies convert the food we eat into energy that we can use. Riboflavin is also important for the growth and development of our cells and helps keep our skin and eyes healthy.

How Does Prednisone Affect Riboflavin?

While prednisone can be effective in managing many conditions, it can have various side effects, including potential impacts on vitamin levels. Prednisone may affect riboflavin levels in several ways. Prednisone can cause riboflavin depletion in the body by increasing the breakdown and excretion of riboflavin. This medication affects the way the body processes and metabolizes riboflavin, leading to lower levels of this nutrient in the body.

How Can Riboflavin Help Someone on Prednisone?

Prednisone can have certain side effects that may affect our bodies. Riboflavin can potentially help mitigate these effects and support overall health. Here’s how:

1. Boosting Energy Levels

Prednisone can sometimes cause fatigue or weakness. Riboflavin helps convert the food we eat into energy, which may help combat these feelings of tiredness and improve overall energy levels.

2. Supporting Cellular Growth and Development

Prednisone can occasionally impact the growth and development of our cells. Riboflavin is necessary for the proper growth and function of our cells, which may help support normal cell development and blood levels while on prednisone.

3. Promoting Healthy Skin and Eyes

Prednisone may cause skin issues like dryness or acne. Riboflavin is essential for healthy skin, as it helps maintain the integrity of our skin cells. Riboflavin also supports the health of our eyes and may help reduce the risk of certain eye problems.

What are the Symptoms of Vitamin B2 Deficiency?

Individuals taking prednisone for an extended period may be at risk of vitamin B2 deficiency. Vitamin B2 (riboflavin) deficiency can lead to a range of symptoms, including sore throat, redness and swelling of the lining of the mouth and throat, cracks or sores on the outsides of the lips, inflammation and redness of the tongue, and a moist, scaly skin inflammation in the area between the scrotum and the anus. A deficiency in riboflavin can impair the absorption and utilization of iron, leading to anemia or iron deficiency.

Which Other Medications Deplete Vitamin B2?

Prednisone is not the only medication that can lead to a decrease in vitamin B2 levels. Some antimalarial drugs, tricyclic antidepressants, and specific oral contraceptives can also deplete B2 reserves. If you find yourself on any of these medications, it’s essential to be mindful of your B2 intake.

How Can Nutranize Zone Help?

Nutranize Zone, containing riboflavin as one of its ingredients, provides a convenient way to ensure you’re getting enough of this essential nutrient. By taking Nutranize Zone while on prednisone, you can potentially support your energy levels, promote healthy cell growth and development, and maintain healthy skin and eyes.

How to Eat More Riboflavin?

Getting enough riboflavin, also known as vitamin B2, is essential for maintaining overall health and well-being. Luckily, there are several easy and delicious ways to incorporate more riboflavin-rich foods into your diet. Here are some helpful tips to help you increase your riboflavin intake:

1. Include dairy products

Dairy products like milk, cheese, and yogurt are excellent sources of riboflavin. Opt for low-fat versions to keep your calorie intake in check. Adding a glass of milk or a yogurt cup to your daily routine can significantly boost your riboflavin levels.

2. Choose lean meats and poultry

Lean meats such as chicken, turkey, and beef are not only rich in protein but also contain good amounts of riboflavin. Incorporate grilled chicken breast, lean cuts of beef, or turkey burgers into your meals to increase your riboflavin intake.

3. Eat more eggs

Eggs are a versatile and nutritious food choice that can help increase your riboflavin intake. Whether you prefer them boiled, scrambled, or in an omelet, eggs are an easy way to add riboflavin to your diet. Additionally, eggs provide many other essential nutrients, making them a great addition to any meal.

4. Explore plant-based sources

If you follow a vegetarian or vegan diet, there are still plenty of plant-based sources of riboflavin available. Incorporate more leafy green vegetables like spinach, asparagus, and broccoli into your meals. Legumes such as lentils and chickpeas are also great options to boost your riboflavin intake.

5. Consume fortified cereals and grains

Many cereals, bread, and pasta products are now fortified with essential vitamins and minerals, including riboflavin. Check the packaging labels to choose options that offer higher riboflavin content. Whole grains like brown rice, quinoa, and oats are also good choices, as they naturally contain riboflavin along with other beneficial nutrients.

6. Include nuts and seeds

Almonds, sunflower seeds, and sesame seeds are not only delicious but also rich in riboflavin. Sprinkle them over salads, cereals, or yogurt for an added crunch and nutrient boost.

7. Be mindful of cooking methods

Riboflavin is a heat-sensitive vitamin, meaning it can be lost during cooking. To retain the maximum amount of riboflavin in your food, opt for steaming, baking, or sautéing over boiling or deep-frying methods.

8. Consider dietary supplements

If you struggle to meet your riboflavin requirements through food alone, dietary supplements can be an option. Consult with a healthcare professional to determine the right dosage and ensure it aligns with your specific needs.

Remember, maintaining a well-balanced diet that incorporates a variety of riboflavin-rich foods is key to meeting your nutritional requirements. By following these tips, you can easily increase your riboflavin intake and enjoy the many health benefits this essential vitamin provides.


Riboflavin is a marvelous nutrient that can help counteract some of the side effects caused by prednisone. By consuming enough riboflavin through Nutranize Zone or riboflavin-rich foods, individuals on prednisone can potentially boost their energy levels, support proper cell growth and development, and promote healthy skin and eyes. Always remember to consult with your healthcare provider before starting any new supplement or making significant changes to your diet.

  1. Sperduto RD, Hu TS, Milton RC, et al. Arch Ophthalmol. 1993;111:1246-53. PMID: 8363468.
For further reading:
  1. 75+ Scientific Articles and Nutranize Zone Ingredients
  2. 9+ Nutrients Depleted by Prednisone